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Maria Francesca Aleo

Researcher at University of Brescia

Publications -  21
Citations -  4824

Maria Francesca Aleo is an academic researcher from University of Brescia. The author has contributed to research in topics: Autophagy & Skeletal muscle. The author has an hindex of 13, co-authored 21 publications receiving 3903 citations. Previous affiliations of Maria Francesca Aleo include Brescia University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Stress proteins and oxidative damage in a renal derived cell line exposed to inorganic mercury and lead.

TL;DR: In NRK-52E cell line the stress response is an early and metal-induced event that correlates well with the direct oxidative damage induced by mercury, and different chaperones are involved in the specific nephrotoxic mechanism of these environmental pollutants and work together for cell survival.
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Cisplatin triggers atrophy of skeletal C2C12 myotubes via impairment of Akt signalling pathway and subsequent increment activity of proteasome and autophagy systems.

TL;DR: Results indicate that cisPt induces atrophy of C2C12 myotubes via activation of proteasome and autophagy systems, suggesting that the Akt pathway represents one sensitive target of cisPT molecular action in skeletal muscle.
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Endogenous thiols and MRP transporters contribute to Hg2+ efflux in HgCl2-treated tubular MDCK cells.

TL;DR: The results demonstrate that, in MDCK cells, inorganic Hg(2+) promotes the activation of specific detoxifying pathways that may, at least partly, depend on the activity of MRP transporters.
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ER signaling regulation drives the switch between autophagy and apoptosis in NRK-52E cells exposed to cisplatin.

TL;DR: This is the first demonstration that taurine enhances autophagic protection against apoptosis by reducing ER stress, thus making it possible to develop new strategies to reduce severe cisPt-induced side-effects such as nephrotoxicity.