Carine Michiels

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Comparing the efficiency of three different antioxidant enzymes: Cu/Zn-superoxide dismutase, catalase, and selenium-glutathione peroxidase shows that all three antioxidant enzymes give protection for the cells, and emphasizes the fact that each enzyme has a specific as well as an irreplaceable function.

TL;DR: Since the three enzymes of the antioxidant system are susceptible to at least one of the oxidative reactive molecules, in the case of high oxidative stresses such an inhibition could take place, leading to an irreversible autocatalytical process in which the production rate of the oxidants will continuously increase,leading to cell death.

TL;DR: The most important endothelial functions will be described, their role in blood vessel formation, in coagulation and fibribolysis, in the regulation of vascular tone as well as their participation in inflammatory reactions and in tumor neoangiogenesis.