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Nathalie M. Mazure

Researcher at University of Nice Sophia Antipolis

Publications -  73
Citations -  13257

Nathalie M. Mazure is an academic researcher from University of Nice Sophia Antipolis. The author has contributed to research in topics: Hypoxia-inducible factors & Hypoxia (medical). The author has an hindex of 36, co-authored 67 publications receiving 11568 citations. Previous affiliations of Nathalie M. Mazure include Stanford University & French Institute of Health and Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Hypoxia signalling in cancer and approaches to enforce tumour regression

TL;DR: There are new approaches to enforce necrotic cell death and tumour regression by targeting tumour metabolism and pHi-control systems.
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Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

TL;DR: A model in which the atypical BH3 domains of hypoxia-induced BNIP3/BNIP3L have been designed to induce autophagy by disrupting the Bcl-2-Beclin1 complex without inducing cell death is proposed.
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Hypoxia-Inducible Carbonic Anhydrase IX and XII Promote Tumor Cell Growth by Counteracting Acidosis through the Regulation of the Intracellular pH

TL;DR: Hypoxia-induced CAIX and CAXII are major tumor prosurvival pH(i)-regulating enzymes, and their combined targeting shows that they hold potential as anticancer targets.
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Hypoxia-induced autophagy: cell death or cell survival?

TL;DR: The autophagic cell death that is often observed in these extreme stress conditions should be seen as the outcome of failed adaptation.