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Valerie Askanas

Researcher at University of Southern California

Publications -  177
Citations -  17752

Valerie Askanas is an academic researcher from University of Southern California. The author has contributed to research in topics: Inclusion body myositis & Myopathy. The author has an hindex of 52, co-authored 177 publications receiving 16192 citations. Previous affiliations of Valerie Askanas include National Institutes of Health.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Inclusion body myositis and myopathies.

Robert C. Griggs, +6 more
- 01 Nov 1995 - 
TL;DR: Newest approaches to diagnosis and pathogenesis of sporadic inclusion-body myositis and hereditary inclusion- body myopathies, including molecular-pathologic similarities to Alzheimer disease are introduced.
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Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

Yan Wang, +10 more
- 27 Mar 2001 - 
TL;DR: The striking tissue specificity of the muscle mtDNA mutations detected here and their mapping at critical sites for mtDNA replication strongly point to the involvement of a specific mutagenic machinery and to the functional relevance of these mutations.
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Inclusion-body myositis A myodegenerative conformational disorder associated with Aβ, protein misfolding, and proteasome inhibition

Valerie Askanas, +1 more
- 24 Jan 2006 - 
TL;DR: It is proposed that the identified abnormal accumulation, misfolding, and aggregation of proteins, perhaps provoked by the aging milieu and aggravated by the oxidative stress, lead to the s-IBM-specific vacuolar degeneration and atrophy of muscle fibers.