Manoj B. Menon

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Several pieces of evidence indicate that the phosphorylation and ubiquitination of BECN1 at an array of residues fine-tune the responses to diverse autophagy modulating stimuli and helps in maintaining the balance between pro-survivalautophagy and pro-apoptotic responses.

TL;DR: MK2 phosphorylation of RIPK1 is a crucial checkpoint for cell fate in inflammation and infection that determines the outcome of bacteria–host cell interaction.

TL;DR: It is demonstrated that MK2/3 also contribute to the de novo synthesis of TTP, and a model is proposed, which demonstrates how this new function of transcriptional activation of T TP by MK 2/3 cooperates with the role of MK2 /3 in post-transcriptional gene expression to limit the inflammatory response.