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Sean T. Sweeney

Researcher at University of York

Publications -  83
Citations -  14431

Sean T. Sweeney is an academic researcher from University of York. The author has contributed to research in topics: Gene & Synapse. The author has an hindex of 30, co-authored 72 publications receiving 12552 citations. Previous affiliations of Sean T. Sweeney include University of Leicester & Hull York Medical School.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects

TL;DR: To further the study of synaptic function in a genetically tractable organism and to generate a tool to disable neuronal communication for behavioural studies, a gene encoding tetanus toxin light chain is expressed in Drosophila.
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Altered electrical properties in Drosophila neurons developing without synaptic transmission

TL;DR: The data suggest that synaptic activity makes little or no contribution to the initial formation of embryonic neural circuits, and the electrical development of neurons that constitute these circuits seems to depend on a process that requires synaptic activity.
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Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila.

TL;DR: It is concluded that the SNARE hypothesis cannot fully explain the role of these proteins in synaptic transmission and instead, both proteins play distinct roles downstream of docking.