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Angelika Amon

Researcher at Massachusetts Institute of Technology

Publications -  201
Citations -  29098

Angelika Amon is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Aneuploidy & Mitotic exit. The author has an hindex of 78, co-authored 200 publications receiving 26171 citations. Previous affiliations of Angelika Amon include Cold Spring Harbor Laboratory & University of California, San Francisco.

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Journal ArticleDOI

Relevance and Regulation of Cell Density.

Gabriel Neurohr, +1 more
- 01 Mar 2020 - 
TL;DR: The recent development of new technologies to accurately measure the cell density of single cells in suspension and in tissues is likely to provide answers to how cell density affects cell function, how it is controlled, and how it sometimes changes as part of a developmental process or in response to changes in the environment.
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Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells.

Christopher M. Brennan, +8 more
- 01 Aug 2019 - 
TL;DR: It is proposed that proteotoxic stress is a universal feature of aneuploid cells and degradation and aggregation of excess polypeptides function as a form of dosage compensation.
Journal ArticleDOI

The FEAR network.

Jeremy M. Rock, +1 more
- 15 Dec 2009 - 
TL;DR: In the budding yeast S. cerevisiae, a signaling network known as the FEAR network is critical to ensure accurate anaphase chromosome segregation and the integration of this process with otherAnaphase events and the potential for conserved FEARnetwork functions in other eukaryotes is discussed.
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Aneuploidy impairs hematopoietic stem cell fitness and is selected against in regenerating tissues in vivo

Sarah J. Pfau, +3 more
- 15 Jun 2016 - 
TL;DR: It is found that aneuploid hematopoietic stem cells (HSCs) exhibit decreased fitness, which indicates that, in vivo, mechanisms exist to select against aneuPLoid cells.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -