Zsuzsanna Szatmári

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Recent advances on the effects of RABs and their upstream modulators in the regulation of autophagy are summarized and how impairment of these proteins alters the autophagic process leading to several generally known human diseases is discussed.

TL;DR: Induction of autophagy appears to promote autophagic flux by increased convergence with the endosomal pathway by removing Hook from mature late endosomes and inhibiting its homodimerization.

TL;DR: An overview of the molecular mechanisms of autophagy is provided and recent advances on its function in human health and disease are summarized.