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Jia Luo

Researcher at University of Kentucky

Publications -  179
Citations -  13336

Jia Luo is an academic researcher from University of Kentucky. The author has contributed to research in topics: Unfolded protein response & Metastasis. The author has an hindex of 51, co-authored 164 publications receiving 12003 citations. Previous affiliations of Jia Luo include United States Department of Health and Human Services & University of Iowa.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Glycogen synthase kinase 3β (GSK3β) in tumorigenesis and cancer chemotherapy

Jia Luo
- 18 Jan 2009 - 
TL;DR: Although GSK3beta is an attractive therapeutic target for a number of human diseases, its potential impact on tumorigenesis and cancer chemotherapy needs to be carefully evaluated.
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Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury.

Man Jiang, +3 more
- 01 Mar 2010 - 
TL;DR: In vivo and in vitro models of ischemia-reperfusion demonstrated autophagy induction during hypoxic and ischemic renal injury and suggested that under these pathological conditions,autophagy may provide a protective mechanism for cell survival.
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Glycogen synthase kinase 3β (GSK3β) mediates 6-hydroxydopamine-induced neuronal death

Gang Chen, +5 more
- 01 Jul 2004 - 
TL;DR: It is demonstrated here that 6‐OHDA evoked endoplasmic reticulum (ER) stress, which was characterized by an up‐regulation in the expression of GRP78 and GADD153 (Chop), cleavage of procaspase‐12, and phosphorylation of eukaryotic initiation factor‐2 a in a human dopaminergic neuronal cell line (SH‐SY5Y) and cultured rat cerebellar granule neurons (CGNs).
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Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways.

Poyil Pratheeshkumar, +12 more
- 18 Oct 2012 - 
TL;DR: The findings in the present study suggest that quercetin inhibits tumor growth and angiogenesis by targeting VEGF-R2 regulated AKT/mTOR/P70S6K signaling pathway, and could be used as a potential drug candidate for cancer therapy.