Sharon Prince

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Results implicate Tbx2 as a novel direct regulator of p21 expression and have implications for the understanding of the role of T-box factors in the regulation of senescence and oncogenesis, as well as in development.

TL;DR: This review presents a state of the art overview of the role and regulation of Tbx2 in early embryonic development and in cancer.

TL;DR: Using deletion constructs and a reporter assay, a functional miRNA site for Hsa-miR-608 within the COL5A1 3'-UTR is identified and additional elements which regulate COL 5A1 mRNA stability are identified which have important implications for the understanding of the molecular basis of musculoskeletal soft tissue injuries and other exercise-related phenotypes.

TL;DR: It is demonstrated, using in vitro and in vivo cell proliferation, as well as colony- and tumor-forming ability and cell motility assays, that TBX2 and TBX3 have distinct roles in melanoma progression and this results have important implications for the development of new cancer treatments.