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Yuguang Shi

Researcher at University of Texas Health Science Center at San Antonio

Publications -  82
Citations -  11187

Yuguang Shi is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Cardiolipin & Kinase. The author has an hindex of 41, co-authored 78 publications receiving 10161 citations. Previous affiliations of Yuguang Shi include McGill University & Penn State Milton S. Hershey Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Identification and characterization of pancreatic eukaryotic initiation factor 2 α-subunit kinase, PEK, involved in translational control

Yuguang Shi, +6 more
- 01 Dec 1998 - 
TL;DR: Using recombinant PEK produced inEscherichia coli or Sf-9 insect cells, it is demonstrated that PEK is autophosphorylated on both serine and threonine residues and that the recombinant enzyme can specifically phosphorylate eIF-2α on serine-51.
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Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity.

Yanyun Chen, +11 more
- 01 Jul 2002 - 
TL;DR: MCHR1 is firmly established as a mediator of MCH effects on energy homeostasis and suggest that inactivation of MCHR1 alone is capable to counterbalance obesity induced by a high-fat diet.
Journal ArticleDOI

Lipid metabolic enzymes: emerging drug targets for the treatment of obesity

Yuguang Shi, +2 more
- 01 Aug 2004 - 
TL;DR: The main enzymes that are involved in different stages of lipid metabolism — from digestion and absorption through synthesis and storage to mobilization and oxidation — which might be successfully targeted by new pharmacotherapies are reviewed.
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Hepatitis C therapeutics: current status and emerging strategies.

Seng-Lai Tan, +3 more
- 01 Nov 2002 - 
TL;DR: The development of effective HCV antiviral therapeutics continues to be a daunting challenge owing to the absence of adequate animal models and tissue-culture systems for analysis and propagation of the virus.