A. Sue Menko

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Chondrocytes isolated from the cephalic region of sterna from 14-day-old chick embryos used beta 1 integrins and required either Mg2+ or Mn2+ for attachment to plates coated with type I collagen, type II collagen, and fibronectin substrates.

TL;DR: Embryonic chicken lenses, which had been disrupted by trypsin, were grown in culture and it was shown that the lentoid cells had many characteristics in common with the differentiated cells of the intact lens, the elongated fiber cells.

TL;DR: The presence of autophagic vesicles containing mitochondria in lens epithelial cells, immature lens fiber cells and during early stages of lens fiber cell differentiation is demonstrated to provide evidence that autophagy occurs throughout the lens and that mitophagy functions in the lens to remove damaged mitochondria from the lens epithelium.

TL;DR: This work induced lens cell differentiation by short-term exposure of lens epithelial cells to the apoptogen staurosporine and discovered that there was high expression in the lens equatorial epithelium of pro-apoptotic molecules such as Bax and Bcl-xS and release of cytochrome c from mitochondria.