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Jae-sung Bae

Researcher at Kyungpook National University

Publications -  142
Citations -  9000

Jae-sung Bae is an academic researcher from Kyungpook National University. The author has contributed to research in topics: Mesenchymal stem cell & Microglia. The author has an hindex of 31, co-authored 129 publications receiving 7881 citations. Previous affiliations of Jae-sung Bae include Gwangju Institute of Science and Technology & University College London.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Intracerebral Transplantation of Bone Marrow‐Derived Mesenchymal Stem Cells Reduces Amyloid‐Beta Deposition and Rescues Memory Deficits in Alzheimer's Disease Mice by Modulation of Immune Responses

Jong Kil Lee, +5 more
- 01 Feb 2010 - 
TL;DR: It is demonstrated that BM‐MSCs can modulate immune/inflammatory responses in AD mice, ameliorate their pathophysiology, and improve the cognitive decline associated with Aβ deposits.
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Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation.

Hyun Ju Lee, +10 more
- 01 Mar 2012 - 
TL;DR: It is suggested that hUCB-MSC produced their sustained neuroprotective effect by inducing a feed-forward loop involving alternative activation of microglial neuroinflammation, thereby ameliorating disease pathophysiology and reversing the cognitive decline associated with Aβ deposition in AD mice.
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Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

Jinyoung Shin, +6 more
- 01 Jan 2014 - 
TL;DR: It is suggested that mesenchymal stem cells significantly enhance autolysosome formation and clearance of Aβ in AD models, which may lead to increased neuronal survival against Aβ toxicity.
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Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model

Jong Kil Lee, +2 more
- 30 Jan 2009 - 
TL;DR: Evidence is provided that BM-MSCs can promote the reduction of Abeta through the microglial activation in this acutely induced AD brain, suggesting a potential therapeutic agent against AD.