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Michael Sacher

Researcher at Concordia University

Publications -  61
Citations -  9438

Michael Sacher is an academic researcher from Concordia University. The author has contributed to research in topics: TRAPP complex & Golgi apparatus. The author has an hindex of 30, co-authored 57 publications receiving 7898 citations. Previous affiliations of Michael Sacher include Yale University & Concordia University Wisconsin.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion

TL;DR: It is proposed that TRAPP plays a key role in the targeting and/or fusion of ER‐to‐Golgi transport vesicles with their acceptor compartment, as well as biochemical studies showing that Bet3p functions on this compartment, support this hypothesis.
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TRAPP I Implicated in the Specificity of Tethering in ER-to-Golgi Transport

TL;DR: Two forms of TRAPP are reported, TRAPP I and TRAPP II, that mediate different transport events and imply that TRAPPI is the receptor on the Golgi for COPII vesicles.
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Protein complexes in transport vesicle targeting

TL;DR: This review focuses on the proteins and protein complexes that have been implicated in various targeting reactions that affect the transport of material between membrane-bounded organelles in eukaryotic cells.