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Shane Deegan

Researcher at National University of Ireland, Galway

Publications -  18
Citations -  6436

Shane Deegan is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Unfolded protein response & Endoplasmic reticulum. The author has an hindex of 14, co-authored 18 publications receiving 5842 citations. Previous affiliations of Shane Deegan include National University of Ireland.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response

Afshin Samali, +3 more
- 19 Jan 2010 - 
TL;DR: Approaches that can be used by researchers to plan and interpret experiments aimed at evaluating whether the Unfolded Protein Response (UPR) and related processes are activated are discussed.
Journal ArticleDOI

Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

Shane Deegan, +3 more
- 01 Jul 2013 - 
TL;DR: Current knowledge regarding how ER stress and the unfolded protein response (UPR) induce autophagy is reviewed, including description of the different autophagic-related genes which are regulated by the UPR.
Journal ArticleDOI

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

Sanjeev Gupta, +5 more
- 06 Jul 2010 - 
TL;DR: The cytosolic chaperone Hsp72 directly modulates stress sensing in response to the accumulation of unfolded proteins in the endoplasmic reticulum and promotes cell survival.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -