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Svetlana Saveljeva

Researcher at University of Cambridge

Publications -  20
Citations -  6687

Svetlana Saveljeva is an academic researcher from University of Cambridge. The author has contributed to research in topics: Unfolded protein response & Endoplasmic reticulum. The author has an hindex of 16, co-authored 19 publications receiving 5882 citations. Previous affiliations of Svetlana Saveljeva include National University of Ireland, Galway.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress

Shane Deegan, +3 more
- 01 Jul 2013 - 
TL;DR: Current knowledge regarding how ER stress and the unfolded protein response (UPR) induce autophagy is reviewed, including description of the different autophagic-related genes which are regulated by the UPR.
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New directions in ER stress-induced cell death

Susan E. Logue, +3 more
- 21 Feb 2013 - 
TL;DR: The role of ER localized proteins in sensing and triggering ER stress-induced death signals with particular emphasis on the contribution of calcium signaling and Bcl-2 family members to the execution phase of this process is highlighted.
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Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis

Markus Tschurtschenthaler, +21 more
- 01 Feb 2017 - 
TL;DR: Defective autophagy in IECs may predispose to CD ileitis via impaired clearance of IRE1&agr; aggregates during ER stress at this site, which aggravates dextran sodium sulfate–induced colitis.
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C13orf31 (FAMIN) is a central regulator of immunometabolic function

M. Zaeem Cader, +23 more
- 01 Sep 2016 - 
TL;DR: FAMIN is identified a central regulator of the metabolic function and bioenergetic state of macrophages that is under evolutionary selection and determines the risk of inflammatory and infectious disease.