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Marc Bitoun

Researcher at University of Paris

Publications -  69
Citations -  7918

Marc Bitoun is an academic researcher from University of Paris. The author has contributed to research in topics: Centronuclear myopathy & Dynamin. The author has an hindex of 29, co-authored 64 publications receiving 7170 citations. Previous affiliations of Marc Bitoun include École Normale Supérieure & Pierre-and-Marie-Curie University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Mutations in dynamin 2 cause dominant centronuclear myopathy.

Marc Bitoun, +13 more
- 16 Oct 2005 - 
TL;DR: In 11 families affected by centronuclear myopathy, recurrent and de novo missense mutations in the gene dynamin 2 (DNM2), which encodes a protein involved in endocytosis and membrane trafficking, actin assembly and centrosome cohesion, were identified.
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Dynamin 2 mutations cause sporadic centronuclear myopathy with neonatal onset.

Marc Bitoun, +18 more
- 01 Dec 2007 - 
TL;DR: The phenotypic spectrum of dynamin 2–related centronuclear myopathy is expanded from the classic mild form to the more severe neonatal phenotype, and electrophysiology and muscle biopsies showed central nuclei and type 1 fiber hypotrophy and predominance.
Journal ArticleDOI

Dynamin 2 and human diseases

Anne-Cécile Durieux, +3 more
- 03 Feb 2010 - 
TL;DR: The molecular, biochemical, and functional data on DNM2 are summarized and the possible pathophysiological mechanisms via which D NM2 mutations can lead to two distinct neuromuscular disorders are discussed.
Journal ArticleDOI

Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy.

Johann Böhm, +67 more
- 01 Jun 2012 - 
TL;DR: The possible clinical overlap of CNM and CMT, and the biological significance of the respective mutations based on the known functions of dynamin 2 and its protein structure are discussed.