Chong Liu

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The present review will describe the structure and mechanisms of activation of the NLRP3 inflammasome, its association with various auto-immune and auto-inflammatory diseases, and the state of research into NLRP2 inflammaome inhibitors.

TL;DR: Accumulating evidence demonstrates that autophagy plays an important role in inhibiting inflammation and apoptosis, and in promoting efferocytosis and cholesterol efflux, and these facts suggest the induction of Autophagy may be exploited as a potential strategy for the treatment of atherosclerosis.

TL;DR: A deficit in the cholinergic anti-inflammatory pathway appears to contribute to the pathogenesis of EOD in models of hypertension of varying etiology, and this pathway may provide a new target for preventing cardiovascular disease resulting from hypertension.

TL;DR: Whether autophagy is involved in the beneficial effect of CB2R on EAE is examined and the mechanism with a focus on inflammasome activation is explored.