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Natascia Ventura

Researcher at University of Düsseldorf

Publications -  68
Citations -  7980

Natascia Ventura is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Caenorhabditis elegans & Mitochondrion. The author has an hindex of 29, co-authored 56 publications receiving 7116 citations. Previous affiliations of Natascia Ventura include University of Colorado Boulder & University of Rome Tor Vergata.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans.

TL;DR: It is shown that a specific signal, initiated during the L3/L4 larval stage of development, is sufficient for initiating mitochondrial dysfunction–dependent life extension in C. elegans, and proposed that cell cycle checkpoint control plays a key role in specifying longevity of mitochondrial mutants.
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The hallmarks of fibroblast ageing

TL;DR: The systematic of ubiquitous hallmarks of ageing is used to categorise the available knowledge regarding dermal fibroblast ageing and discriminate processes inducible in culture from phenomena apparent in skin biopsies or primary cells from old donors, coming to the following conclusions.
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Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans.

TL;DR: The findings indicate that mitophagy induction is part of an adaptive iron starvation response induced as a protective mechanism against mitochondrial stress, thus suggesting novel potential therapeutic strategies for the treatment of mitochondrial-associated, age-related disorders.
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In vivo maturation of human frataxin

TL;DR: The data indicate that frataxin(56-210) can be produced in vivo when the primary 80-81 maturation site is unavailable, suggesting the existence of proteolytic mechanisms that can actively control the size of the mature product, with possible functional implications.