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Dohun Pyeon

Researcher at University of Colorado Denver

Publications -  54
Citations -  7654

Dohun Pyeon is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 22, co-authored 45 publications receiving 6820 citations. Previous affiliations of Dohun Pyeon include University of Wisconsin-Madison & Wisconsin Alumni Research Foundation.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Fundamental differences in cell cycle deregulation in human papillomavirus-positive and human papillomavirus-negative head/neck and cervical cancers.

TL;DR: Findings in primary human tumors provide novel biomarkers for early detection of HPV(+) and HPV(-) cancers, and emphasize the potential value of targeting E6 and E7 function, alone or combined with radiation and/or traditional chemotherapy, in the treatment of HPV (+) cancers.
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Establishment of Human Papillomavirus Infection Requires Cell Cycle Progression

TL;DR: Chemical biology approaches are used to reveal that cell cycle progression through mitosis is critical for HPV infection, and provide one reason why HPVs initially establish infections in the basal compartment of stratified epithelia.
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Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

TL;DR: A dramatic, progressive decrease in estrogen receptor alpha (ERα) in tumor progression is observed, and ranking specimens by estrogen-responsive gene expression correlated remarkably with histopathology, implying that estrogen signaling increasingly proceeds indirectly through ERα in tumor-associated stromal fibroblasts.
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APOBEC3A Functions as a Restriction Factor of Human Papillomavirus

TL;DR: HA3A and hA3B expression levels are highly upregulated in HPV-positive keratinocytes and cervical tissues in early stages of cancer progression, and the induction of this host restriction mechanism by HPV may come at a cost to the host by promoting cancer mutagenesis.