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Kathleen W. Scotto

Researcher at Rutgers University

Publications -  51
Citations -  10080

Kathleen W. Scotto is an academic researcher from Rutgers University. The author has contributed to research in topics: Dihydrofolate reductase & Promoter. The author has an hindex of 30, co-authored 51 publications receiving 8579 citations. Previous affiliations of Kathleen W. Scotto include Memorial Sloan Kettering Cancer Center & Fox Chase Cancer Center.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

Ron Bose, +5 more
- 11 Aug 1995 - 
TL;DR: It is demonstrated that ceramide synthase activity can be regulated in eukaryotes and constitute definitive evidence for a requirement for ceramide elevation in the induction of apoptosis.
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Transcriptional Regulation of the MDR1 Gene by Histone Acetyltransferase and Deacetylase Is Mediated by NF-Y

Shengkan Jin, +1 more
- 01 Jul 1998 - 
TL;DR: It is demonstrated that HAT and HDAC activities modulate transcription of the P-glycoprotein-encoding gene, MDR1, the first report of a natural promoter that is modulated by H AT and HDac activities in which the transcription factor mediating this regulation has been identified.
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Amplification and expression of genes associated with multidrug resistance in mammalian cells

Kathleen W. Scotto, +2 more
- 09 May 1986 - 
TL;DR: In Chinese hamster cells, the development of resistance to a single drug and multidrug resistance were closely related, but uncoupled, events, and the overexpression of theMultidrug-resistant genes was better correlated with the degree of Resistance to the selective agent than it was with the extent of multidrog resistance.