Andrei S. Chagin

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Current clinical approaches for repairing cartilage, as well as research approaches which are currently developing, and those under translation into clinical practice are discussed, and potential future directions in this area are described, including tissue engineering based on scaffolding and/or stem cells aswell as a combination of gene and cell therapy.

TL;DR: In this article, the effects of Dexamethasone (Dexa) on apoptosis in the HCS-2/8 chondrocytic cell line were studied.

TL;DR: It is demonstrated that, in mice, longitudinal bone growth during fetal and neonatal periods relies on the gradual consumption of chondroprogenitors, whereas in adults, a stem cell niche is formed allowing renewing ofChondro Progenitors and leading to formation of large, stable monoclonal columns of chONDrocytes.