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Alireza R. Rezaie

Researcher at Oklahoma Medical Research Foundation

Publications -  198
Citations -  12102

Alireza R. Rezaie is an academic researcher from Oklahoma Medical Research Foundation. The author has contributed to research in topics: Thrombin & Protein C. The author has an hindex of 46, co-authored 196 publications receiving 11176 citations. Previous affiliations of Alireza R. Rezaie include University of Oklahoma Health Sciences Center & Saint Louis University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

Jong-Sup Bae, +3 more
- 01 Dec 2007 - 
TL;DR: It is demonstrated that EPCR is associated with caveolin-1 in lipid rafts of endothelial cells and that its occupancy by the gamma-carboxyglutamic acid (Gla) domain of protein C/APC leads to its dissociation from Caveolin- 1 and recruitment of PAR-1 to a protective signaling pathway through coupling of PAR -1 to the pertussis toxin-sensitive G(i)-protein.
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Protein C Inhibitor Is a Potent Inhibitor of the Thrombin-Thrombomodulin Complex

Alireza R. Rezaie, +5 more
- 27 Oct 1995 - 
TL;DR: Thrombin-binding proteoglycan, rabbit thrombomodulin, accelerates inhibition of thrombin by PCI and indicates that PCI is a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition.
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Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

Jong-Sup Bae, +2 more
- 20 Feb 2007 - 
TL;DR: It is demonstrated that the critical receptors required for both protein C activation and EPCR and APC cellular signaling pathways are colocalized in the membrane lipid rafts in endothelial cells, which provides a plausible answer to how APC can elicit protective cellular responses through the activation of PAR-1 when thrombin is present.
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The Endothelial Cell Protein C Receptor CELL SURFACE EXPRESSION AND DIRECT LIGAND BINDING BY THE SOLUBLE RECEPTOR

Kenji Fukudome, +6 more
- 19 Jul 1996 - 
TL;DR: EPCR is a type 1 transmembrane protein that binds directly to APC, and direct binding between soluble EPCR and protein C/APC is demonstrated.