scispace - formally typeset
J

Jun Hee Lee

Researcher at University of Michigan

Publications -  107
Citations -  14261

Jun Hee Lee is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 41, co-authored 77 publications receiving 11402 citations. Previous affiliations of Jun Hee Lee include KAIST & University of California, San Diego.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

Eek Joong Park, +8 more
- 22 Jan 2010 - 
TL;DR: It is demonstrated that either dietary or genetic obesity is a potent bona fide liver tumor promoter in mice and obesity-promoted HCC development was dependent on enhanced production of the tumor-promoting cytokines IL-6 and TNF, which cause hepatic inflammation and activation of the oncogenic transcription factor STAT3.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

Jun Hee Lee, +10 more
- 05 Mar 2010 - 
TL;DR: Drosophila sestrin dSesn appears to be a negative feedback regulator of TOR that integrates metabolic and stress inputs and prevents pathologies caused by chronic TOR activation that may result from diminished autophagic clearance of damaged mitochondria, protein aggregates, or lipids.
Journal ArticleDOI

Energy-dependent regulation of cell structure by AMP-activated protein kinase

Jun Hee Lee, +10 more
- 21 Jun 2007 - 
TL;DR: The first animal model with no AMPK activity is generated and physiological functions of the kinase are discovered, demonstrating that AMPK has highly conserved roles across metazoan species not only in the control of metabolism, but also in the regulation of cellular structures.