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Daret K. St. Clair

Researcher at University of Kentucky

Publications -  221
Citations -  21272

Daret K. St. Clair is an academic researcher from University of Kentucky. The author has contributed to research in topics: Oxidative stress & Mitochondrion. The author has an hindex of 63, co-authored 210 publications receiving 18402 citations. Previous affiliations of Daret K. St. Clair include Brigham and Women's Hospital & Harvard University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction

Jeffrey N. Keller, +9 more
- 15 Jan 1998 - 
TL;DR: The data suggest that mitochondrial superoxide accumulation and consequent peroxynitrite production and mitochondrial dysfunction play pivotal roles in neuronal apoptosis induced by diverse insults in cell culture and in vivo.
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Regulation of superoxide dismutase genes: implications in disease.

Lu Miao, +1 more
- 15 Aug 2009 - 
TL;DR: Evaluation of nucleotide sequences reveals that regulatory elements of the sod2 gene reside in both the noncoding and the coding region, and changes associated with sod2 lead to alterations in expression levels as well as protein function.
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ROS and p53: A versatile partnership

Bin Liu, +2 more
- 15 Apr 2008 - 
TL;DR: The newly discovered role of p53 in regulating cellular ROS generation and how ROS modulate selective transactivation of certain p53 target genes are examined, with a focus on interlinks between ROS and p53.