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Darius J.R. Lane

Researcher at Florey Institute of Neuroscience and Mental Health

Publications -  73
Citations -  9403

Darius J.R. Lane is an academic researcher from Florey Institute of Neuroscience and Mental Health. The author has contributed to research in topics: Metastasis suppressor & Transferrin. The author has an hindex of 35, co-authored 66 publications receiving 8252 citations. Previous affiliations of Darius J.R. Lane include Monash University & University of Sydney.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.

Des R. Richardson, +7 more
- 15 Jun 2010 - 
TL;DR: This finding has revealed the ability of the mitochondrion to modulate whole-cell iron-processing to satisfy its own requirements for the crucial processes of heme and ISC synthesis.
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Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.

Darius J.R. Lane, +7 more
- 01 May 2015 - 
TL;DR: Major aspects of the journey of iron from its initial cellular uptake, its modes of trafficking within cells, to an overview of its downstream utilization in the cytoplasm and within mitochondria are discussed.
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The active role of vitamin C in mammalian iron metabolism: Much more than just enhanced iron absorption!

Darius J.R. Lane, +1 more
- 01 Oct 2014 - 
TL;DR: Evidence strongly suggests that in addition to the known ability of dietary ascorbate to enhance nonheme iron absorption in the gut, asCorbate within mammalian systems can regulate cellular iron uptake and metabolism, and is a novel modulator of the classical transferrin-iron uptake pathway.
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Mammalian Iron Homeostasis in Health and Disease: Uptake, Storage, Transport, and Molecular Mechanisms of Action

Alfons Lawen, +1 more
- 03 Jun 2013 - 
TL;DR: The various pathways of cellular iron uptake, cellular iron storage, and transport are discussed and recent advances in understanding the reduction and uptake of non-transferrin-bound iron are discussed.