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Candece L. Gladson

Researcher at Cleveland Clinic

Publications -  77
Citations -  9994

Candece L. Gladson is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Integrin & Focal adhesion. The author has an hindex of 41, co-authored 74 publications receiving 9326 citations. Previous affiliations of Candece L. Gladson include Case Western Reserve University & Cleveland Clinic Lerner Research Institute.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Inhibition of Cystine Uptake Disrupts the Growth of Primary Brain Tumors

Wook Joon Chung, +6 more
- 03 Aug 2005 - 
TL;DR: Sulfasalazine was able to reduce glutathione levels in tumor tissue and slow tumor growth in vivo in a commonly used intracranial xenograft animal model for human gliomas when administered by intraperitoneal injection.
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New concepts regarding focal adhesion kinase promotion of cell migration and proliferation.

Braden D. Cox, +3 more
- 01 Sep 2006 - 
TL;DR: The ability of FAK to integrate integrin and growth factor signals resulting in synergistic promotion of cell migration and proliferation, and its potential regulation by nuclear factor kappa B and p53 and a ubiquitously expressed inhibitory protein, suggest that it is remarkable in its capacity to integrate multiple extracellular and intracellular stimuli.
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The Pathobiology of Glioma Tumors

Candece L. Gladson, +2 more
- 15 Jan 2010 - 
TL;DR: The mechanisms that have been implicated in the pathogenesis of the gliomas are reviewed and examples of the cooperative nature of the pathways involved are provided, which may influence the initial therapeutic response and the potential for development of resistance.
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Preterm Fetal Hypoxia-Ischemia Causes Hypertonia and Motor Deficits in the Neonatal Rabbit: A Model for Human Cerebral Palsy?

Matthew Derrick, +10 more
- 07 Jan 2004 - 
TL;DR: A rabbit model of in utero placental insufficiency is reported, in which hypertonia is accompanied by marked abnormalities in motor control, and a unique behavioral model is provided to define mechanisms and sequelae of perinatal brain injury from antenatal hypoxia-ischemia.