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Kenneth L. van Golen

Researcher at University of Delaware

Publications -  71
Citations -  9882

Kenneth L. van Golen is an academic researcher from University of Delaware. The author has contributed to research in topics: RhoC GTP-Binding Protein & Inflammatory breast cancer. The author has an hindex of 35, co-authored 68 publications receiving 9209 citations. Previous affiliations of Kenneth L. van Golen include Christiana Care Health System & University of Michigan.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.

Quintin Pan, +11 more
- 01 Sep 2002 - 
TL;DR: This study reports that copper deficiency induced by tetrathiomolybdate significantly impairs tumor growth and angiogenesis in two animal models of breast cancer: an inflammatory breast cancer xenograft in nude mice and Her2/neu cancer-prone transgenic mice.
Journal Article

RhoC GTPase, a Novel Transforming Oncogene for Human Mammary Epithelial Cells That Partially Recapitulates the Inflammatory Breast Cancer Phenotype

Kenneth L. van Golen, +4 more
- 15 Oct 2000 - 
TL;DR: Data indicate that RhoC GTPase is a transforming oncogene in human mammary epithelial cells and can lead to a highly invasive phenotype, akin to that seen in IBC.
Journal Article

A Novel Putative Low-Affinity Insulin-like Growth Factor-binding Protein, LIBC (Lost in Inflammatory Breast Cancer), and RhoC GTPase Correlate with the Inflammatory Breast Cancer Phenotype

Kenneth L. van Golen, +9 more
- 01 Sep 1999 - 
TL;DR: This study suggests two new molecular markers specific for inflammatory breast cancer, RhoC GTPase and LIBC, which are highly correlated with the inflammatory phenotype when a panel of archival inflammatory breast cancers was compared with noninflammatory stage III breast cancers by in situ hybridization.
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Stepping out of the flow: capillary extravasation in cancer metastasis

Fayth L. Miles, +3 more
- 01 Jan 2008 - 
TL;DR: Leukocyte extravasation during the inflammatory response has provided a model for transendothelial migration (TEM) of cancer cells and some progress has been made in understanding the specific roles of the Rho GTPase family, though much is still unknown.