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Maria F. Czyzyk-Krzeska

Researcher at United States Department of Veterans Affairs

Publications -  67
Citations -  9485

Maria F. Czyzyk-Krzeska is an academic researcher from United States Department of Veterans Affairs. The author has contributed to research in topics: Tyrosine hydroxylase & Gene expression. The author has an hindex of 33, co-authored 63 publications receiving 8858 citations. Previous affiliations of Maria F. Czyzyk-Krzeska include University of Cincinnati Academic Health Center & University of North Carolina at Chapel Hill.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.

Takumi Kamura, +5 more
- 12 Sep 2000 - 
TL;DR: Development of methods for production of the purified recombinant VHL complex are reported and direct biochemical evidence that it can function with an E1 ubiquitin-activating enzyme and E2 ubiqu itin-conjugating enzyme to activate HIF1alpha ubiquitination in vitro is presented.
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VHL-regulated MiR-204 suppresses tumor growth through inhibition of LC3B-mediated autophagy in renal clear cell carcinoma.

Olga Mikhaylova, +12 more
- 17 Apr 2012 - 
TL;DR: It is shown that miR-204 is a VHL-regulated tumor suppressor acting by inhibiting macroautophagy, with MAP1LC3B ( LC3B) as a direct and functional target.
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Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells.

Maria F. Czyzyk-Krzeska, +3 more
- 07 Jan 1994 - 
TL;DR: It is reported that TH gene expression in the rat pheochromocytoma cell line (PC12) is regulated during hypoxia in a manner similar to that measured in carotid body type I cells.
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von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.

Anna V. Kuznetsova, +8 more
- 04 Mar 2003 - 
TL;DR: In this paper, the authors identified regions of Rpb1 and the adjacent subunit 6 of RNA polymerase II (Rpb6) that share sequence and structural similarity with the domain of hypoxia-inducible transcription factor 1α that binds von Hippel-Lindau tumor suppressor protein (pVHL).