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Mustapha Kandouz

Researcher at Wayne State University

Publications -  46
Citations -  7044

Mustapha Kandouz is an academic researcher from Wayne State University. The author has contributed to research in topics: Cancer & Gene expression. The author has an hindex of 24, co-authored 46 publications receiving 6460 citations. Previous affiliations of Mustapha Kandouz include French Institute of Health and Medical Research & Jewish General Hospital.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal Article

Mechanisms Controlling Cell Cycle Arrest and Induction of Apoptosis after 12-Lipoxygenase Inhibition in Prostate Cancer Cells

TL;DR: Results show that the 12-LOX pathway is a critical regulator of prostate cancer progression and apoptosis, by affecting various proteins regulating these processes, and inhibition of 12- LOX is a potential therapeutic agent in the treatment of prostatecancer.
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Proapoptotic effects of antiestrogens, progestins and androgen in breast cancer cells.

TL;DR: It is demonstrated that antiestrogens, progestins, and androgens can promote apoptosis in breast cancer cells, an effect which could be of importance in the therapeutic prevention of breast cancer.
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Gap junctions and connexins as therapeutic targets in cancer.

TL;DR: This article reviews the various strategies that take advantage of gap junctions and connexins to eliminate cancer cells, including use of the bystander effect in gene therapy, the effect of connexin on chemosensitization, the role of apoptotic processes and interactions with the microenvironment.
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Antagonism between estradiol and progestin on BCL-2 expression in breast-cancer cells

TL;DR: The existence of hormonal regulation of Bcl‐2 expression is inferred and a novel role for estradiol and progestin in the genesis of breast cancer is evoked.