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Angel Ortega

Researcher at University of Valencia

Publications -  57
Citations -  9778

Angel Ortega is an academic researcher from University of Valencia. The author has contributed to research in topics: Glutathione & Cancer. The author has an hindex of 33, co-authored 57 publications receiving 8678 citations. Previous affiliations of Angel Ortega include Hospital General Universitario Gregorio Marañón.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Glutathione in Cancer Biology and Therapy

José M. Estrela, +2 more
- 01 Jan 2006 - 
TL;DR: An analysis of links among GSH, adaptive responses to stress, molecular mechanisms of invasive cancer cell survival and death, and sensitization of metastatic cells to therapy shows that acceleration of GSH efflux facilitates selective GSH depletion in metastasis cells.
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Inhibition of cancer growth by resveratrol is related to its low bioavailability.

Miguel Asensi, +6 more
- 01 Aug 2002 - 
TL;DR: The antimetastatic mechanism involves a t-RES (1 microM)-induced inhibition of vascular adhesion molecule 1 (VCAM-1) expression in the hepatic sinusoidal endothelium (HSE), which consequently decreased in vitro B16M cell adhesion to the endothelia via very late activation antigen 4 (VLA-4).
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Oxidative stress in environmental-induced carcinogenesis.

Salvador Mena, +2 more
- 31 Mar 2009 - 
TL;DR: It is important to remark that, in agreement with present knowledge, oxidative/nitrosative/metabolic stress, inflammation, senescence, and cancer are linked concepts that must be discussed in a coordinated manner.
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PGC-1α, Inflammation, and Oxidative Stress: An Integrative View in Metabolism.

Sergio Rius-Pérez, +4 more
- 09 Mar 2020 - 
TL;DR: In conclusion, PGC-1α acts as an essential node connecting metabolic regulation, redox control, and inflammatory pathways, and it is an interesting therapeutic target that may have significant benefits for a number of metabolic diseases.