Hana Schmeisser

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: The interaction of IFN-α/β with its receptor components results in the activation of a number of signaling pathways and the regulation of specific genes and proteins contributes to the numerous biological functions of Type I IFNs.

TL;DR: A new function of type I IFN as an inducer of autophagy is highlighted, which may play an important role in viral clearance, antigen presentation, inhibition of proliferation, as well as a positive feedback loop for the production of type II IFN.

TL;DR: It is shown that the DENV C protein interacts and colocalizes with the multifunctional host protein nucleolin (NCL), and this interaction can be disrupted by the addition of an NCL binding aptamer (AS1411).

TL;DR: A novel function of type I IFN is demonstrated as an inducer of autophagy in multiple cell lines, as indicated by an increase of autophile markers MAP1LC3-II, ATG12–ATG5 complexes, and a decrease of SQSTM1 expression.