Vasilis J. Promponas

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: A novel method that predicts transmembrane domains in proteins using solely information contained in the sequence itself, refines a standard hydrophobicity analysis with a detection of potential termini ('edges', starts and ends) of trans Membrane regions.

TL;DR: A review of the problems associated with tandem repeat sequences that originate from different stages during the sequencing-assembly-annotation-deposition workflow, and that may proliferate in public database repositories affecting all downstream analyses, to raise the awareness level within the community of database users and alert scientists working in the underlying workflow of database creation.

TL;DR: A novel algorithm for low-complexity region detection and selective masking based on multiple-pass Smith-Waterman comparison of the query sequence against twenty homopolymers with infinite gap penalties that is sufficient for masking database query sequences without generating false positives.