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Renwick C. J. Dobson

Researcher at University of Canterbury

Publications -  180
Citations -  11413

Renwick C. J. Dobson is an academic researcher from University of Canterbury. The author has contributed to research in topics: Dihydrodipicolinate synthase & Active site. The author has an hindex of 34, co-authored 161 publications receiving 9132 citations. Previous affiliations of Renwick C. J. Dobson include University of Auckland & La Trobe University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, +43 more
- 19 Sep 2013 - 
TL;DR: Structural-guided mutation of the MLKL pseudoactive site resulted in constitutive, RIPK3-independent necroptosis, demonstrating that modification ofMLKL is essential for propagation of the ne croptosis pathway downstream of RIPK 3.
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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M Hildebrand, +22 more
- 21 Oct 2014 - 
TL;DR: It is shown that the MLKL pseudokinase domain acts as a latch to restrain the N-terminal four-helix bundle (4HB) domain and that unleashing this domain results in formation of a high-molecular-weight, membrane-localized complex and cell death.
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A Three-Ring circus: Metabolism of the three proteogenic aromatic amino acids and their role in the health of plants and animals

Anutthaman Parthasarathy, +6 more
- 06 Apr 2018 - 
TL;DR: The past development and current potential for interventions including the development of herbicides and antibiotics that target key enzymes in AAA-related pathways, as well as AAA-linked secondary metabolism leading to antimicrobials are discussed.