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Shigeko Yamashiro

Researcher at Rutgers University

Publications -  51
Citations -  10153

Shigeko Yamashiro is an academic researcher from Rutgers University. The author has contributed to research in topics: Fascin & Mitosis. The author has an hindex of 37, co-authored 51 publications receiving 9525 citations. Previous affiliations of Shigeko Yamashiro include Vanderbilt University & Harvard University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

TL;DR: It is found that MLC phosphorylation is both necessary and sufficient for the assembly of stress fibers and focal adhesions in 3T3 fibroblasts, suggesting that ROCK and MLCK play distinct roles in spatial regulation of MLCosphorylation.
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Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts

TL;DR: It is suggested that myosin II activated by MLCK at the cell periphery controls membrane ruffling, and that the spatial regulation of MLC phosphorylation plays critical roles in controlling cell migration of fibroblasts.
Journal ArticleDOI

Fascin, an Actin-bundling Protein, Induces Membrane Protrusions and Increases Cell Motility of Epithelial Cells

TL;DR: The results together suggest that fascin is directly responsible for membrane protrusions through reorganization of the microfilament cytoskeleton at the cell periphery via microinjection into LLC-PK1 cells.
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Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells.

TL;DR: Observations suggest that peripheral microfilaments at the edge are involved in force production to drive the cell margin forward while microfilament bundles in cell–cell contacts play a structural role.