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Grant R. Campbell

Researcher at University of California, San Diego

Publications -  46
Citations -  7887

Grant R. Campbell is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 26, co-authored 42 publications receiving 7075 citations. Previous affiliations of Grant R. Campbell include Boston Children's Hospital & Centre national de la recherche scientifique.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Identification of a candidate therapeutic autophagy-inducing peptide

Sanae Shoji-Kawata, +29 more
- 14 Feb 2013 - 
TL;DR: Through the characterization of a domain of beclin 1 that interacts with HIV-1 Nef, an autophagy-inducing peptide is developed that has potential efficacy in the treatment of human diseases.
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Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy

Grant R. Campbell, +2 more
- 10 May 2012 - 
TL;DR: A biological explanation for the benefits and importance of vitamin D sufficiency in HIV and M. tuberculosis-infected persons is provided, and new insights into novel approaches to prevent and treat HIV infection and related opportunistic infections are provided.
Journal ArticleDOI

Hormonally Active Vitamin D3 (1α,25-Dihydroxycholecalciferol) Triggers Autophagy in Human Macrophages That Inhibits HIV-1 Infection

Grant R. Campbell, +2 more
- 27 May 2011 - 
TL;DR: It is found that physiologically relevant concentrations of 1α,25-dihydroxycholecalciferol induce autophagy in human macrophages through a phosphatidylinositol 3-kinase-, ATG-5-, and Beclin-1-dependent mechanism that significantly inhibits HIV-1 replication in a dose-dependent manner.
Journal ArticleDOI

Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration

Grant R. Campbell, +3 more
- 26 Jun 2015 - 
TL;DR: To the authors' knowledge, this is the first report of a virus modulating TFEB localization and helps to explain how HIV modulates autophagy to promote its own replication and cell survival.