Kei Watase

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: Homozygous mice deficient in GLT-1, a widely distributed astrocytic glutamate transporter, show lethal spontaneous seizures and increased susceptibility to acute cortical injury, which can be attributed to elevated levels of residual glutamate in the brains of these mice.

TL;DR: Results indicate that GLAST plays active roles both in the cerebellar climbing fibre synapse formation and in preventing excitotoxic Cerebellar damage after acute brain injury.

TL;DR: It is demonstrated that GLAST is required for normal signal transmission between photoreceptors and bipolar cells and that both GLAST and GLT-1 play a neuroprotective role during ischemia in the retina.

TL;DR: Lithium treatment attenuated the reduction of dendritic branching in mutant hippocampal pyramidal neurons and restored the levels of isoprenylcysteine carboxyl methyltransferase (Icmt), down-regulation of which is an early marker of mutant ATXN1 toxicity.