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Christian Sell

Researcher at Drexel University

Publications -  99
Citations -  15242

Christian Sell is an academic researcher from Drexel University. The author has contributed to research in topics: Senescence & Growth factor. The author has an hindex of 36, co-authored 96 publications receiving 13442 citations. Previous affiliations of Christian Sell include Lankenau Institute for Medical Research & Thomas Jefferson University.

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Journal ArticleDOI

Dissociation of Mitogenesis and Transforming Activity by C-Terminal Truncation of the Insulin-like Growth Factor-I Receptor

Ewa Surmacz, +7 more
- 01 May 1995 - 
TL;DR: It is concluded that the 108 amino acids of the IGF-I receptor are not essential for a mitogenic response to IGF- I, but are required for transformation (as assessed by the ability to grow in soft agar), indicating that these two functions can be dissociated at an intramolecular level.
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Failure of senescent human fibroblasts to express the insulin-like growth factor-1 gene

Andres Ferber, +9 more
- 25 Aug 1993 - 
TL;DR: It is shown that senescent cells fail to express insulin-like growth factor-1 (IGF-1) mRNA, which is expressed in moderate amounts by young cells, which can be ascribed, at least in part, to a transcriptional mechanism.
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Fate of microglia during HIV-1 infection: From activation to senescence?

Natalie C. Chen, +4 more
- 01 Mar 2017 - 
TL;DR: It is proposed that the functions of human microglia evolve during both healthy and pathological aging.
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Aberrant mTOR activation in senescence and aging: A mitochondrial stress response?

Timothy Nacarelli, +2 more
- 01 Aug 2015 - 
TL;DR: The possibility that activation of the mTOR/p70S6K kinase pathway may represent a ROS-mediated response to mitochondrial stress leading to the activation of senescence is explored.
Journal Article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2459 more
- 01 Jan 2016 -