Surajit Sarkar

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: The absence of early meiotic stages in the Hsp60C1 homozygous testes contrasts with the effect of testis-specificHsp60B (21D) gene, whose mutation affects individualization of sperm bundles later in spermiogenesis, and it is likely that, besides its functions as a chaperone, HSp60C may have signalling functions and may also be involved in cation transport across the developing tracheal epithelial cells.

TL;DR: It is shown for the first time that targeted overexpression of Drosophila Myc (dMyc) mitigates the poly(Q) toxicity in eye and nervous systems and provides a rational justification of the enigma of poly(Z) patients showing resistance to the predisposition of cancer.

TL;DR: A brief overview of various Hsps is provided and their involvement in diverse biological activities such as cellular communication, immune response, protein transport, apoptosis, cell cycle regulation, gametogenesis and aging are summarized.

TL;DR: It is demonstrated that tissue-specific downregulation of the Drosophila homolog of human c-myc proto-oncogene (dMyc) suppresses tau-mediated morphological and functional deficits by reducing abnormal tau hyperphosphorylation and restoring the heterochromatin loss.