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Norihiko Furuya

Researcher at Juntendo University

Publications -  28
Citations -  5316

Norihiko Furuya is an academic researcher from Juntendo University. The author has contributed to research in topics: Autophagy & Mitochondrion. The author has an hindex of 18, co-authored 27 publications receiving 3989 citations. Previous affiliations of Norihiko Furuya include Niigata University & University of Tokyo.

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Journal ArticleDOI

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, +11 more
- 15 Dec 2003 - 
TL;DR: It is shown that heterozygous disruption of beclin 1 increases the frequency of spontaneous malignancies and accelerates the development of hepatitis B virus-induced premalignant lesions, providing genetic evidence that autophagy is a novel mechanism of cell-growth control and tumor suppression.
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function.

Norihiko Furuya, +4 more
- 17 Jan 2005 - 
TL;DR: An evolutionarily conserved domain of Beclin 1 is identified that is essential for Vps34 interaction, autophagy function, and tumor suppressor function and a connection between BeClin 1-associated Class III PI-3 kinase-dependent autphagy, but not VPS, function is suggested.
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CHCHD2 mutations in autosomal dominant late-onset Parkinson's disease: a genome-wide linkage and sequencing study

Manabu Funayama, +24 more
- 01 Mar 2015 - 
TL;DR: CHCHD2 mutations are associated with, and might be a cause of, autosomal dominant Parkinson's disease, and further functional studies are needed to understand how mutant CHCHD 2 might play a part in the pathophysiology of Parkinson's Disease.
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Liver autophagy contributes to the maintenance of blood glucose and amino acid levels.

Junji Ezaki, +20 more
- 01 Jul 2011 - 
TL;DR: In mice, liver autophagy makes a significant contribution to the maintenance of blood glucose by converting amino acids to glucose via gluconeogenesis, and this results are the first to show that liver-specific autophagic proteolysis plays a role in blood glucose regulation.