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Jack Wong

Researcher at Shenzhen University

Publications -  16
Citations -  2137

Jack Wong is an academic researcher from Shenzhen University. The author has contributed to research in topics: Apolipoprotein E & Cholesterol. The author has an hindex of 12, co-authored 13 publications receiving 1198 citations. Previous affiliations of Jack Wong include University of California, Los Angeles & Nanjing University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice

TL;DR: Results indicate that 5-LO contributes importantly to the atherogenic process and they provide strong presumptive evidence that reduced 5- LO expression is partly responsible for the resistance to atherosclerosis in CON6 mice.
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Heme Oxygenase-1 Expression in Macrophages Plays a Beneficial Role in Atherosclerosis

TL;DR: It is concluded that HO-1 expression in macrophages constitutes an important component of the antiatherogenic effect by increasing antioxidant protection and decreasing the inflammatory component of atherosclerotic lesions.
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Genetic Locus in Mice That Blocks Development of Atherosclerosis Despite Extreme Hyperlipidemia

TL;DR: The identification of a locus for aortic lesion formation on mouse chromosome 6 that exhibits a highly significant lod score of 6.7 is reported, which was confirmed by constructing a congenic strain in which the chromosome 6 segment from CAST/Ei was transferred to a C57BL/6J background in a series of backcrosses.
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Genetic control of HDL levels and composition in an interspecific mouse cross (CAST/Ei × C57BL/6J)

TL;DR: Low HDL lipid levels exhibited complex inheritance, as 12 quantitative trait loci with significant or suggestive likelihood of observed data scores were identified and novel genes are likely to be important in the control of HDL metabolism.