scispace - formally typeset
J

Joshua P. Gray

Researcher at University of Texas MD Anderson Cancer Center

Publications -  55
Citations -  2413

Joshua P. Gray is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Oxidative stress & Cytochrome P450 reductase. The author has an hindex of 20, co-authored 51 publications receiving 1375 citations. Previous affiliations of Joshua P. Gray include University of South Florida & United States Coast Guard Academy.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Mechanisms Mediating the Vesicant Actions of Sulfur Mustard after Cutaneous Exposure

Michael P. Shakarjian, +9 more
- 01 Mar 2010 - 
TL;DR: Successful therapy for SM poisoning will depend on following new mechanistic leads to develop drugs that target one or more of its sites of action, as well as potential mechanisms mediating its actions.
Journal ArticleDOI

Application of the Amplex Red/Horseradish Peroxidase Assay to Measure Hydrogen Peroxide Generation by Recombinant Microsomal Enzymes

Vladimir Mishin, +4 more
- 01 Jun 2010 - 
TL;DR: It is demonstrated that cytochrome P450s are a major source of hydrogen peroxide in the recombinant cyto Chrome P450 monooxygenase system, and substrate binding is not required for the cy tochrome P 450s to generate reactive oxygen species.
Journal ArticleDOI

Redox cycling and increased oxygen utilization contribute to diquat-induced oxidative stress and cytotoxicity in Chinese hamster ovary cells overexpressing NADPH-cytochrome P450 reductase.

Karma C. Fussell, +6 more
- 01 Apr 2011 - 
TL;DR: Diquat redox cycling in CHO cells was associated with marked increases in protein carbonyl formation, a marker of protein oxidation, as well as cellular oxygen consumption, measured using oxygen microsensors; greater activity was detected in CHO-OR cells than in CHO
Journal ArticleDOI

Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat.

Adrienne T. Black, +5 more
- 15 Sep 2008 - 
TL;DR: It is found that paraquat readily undergoes redox cycling in both undifferentiated and differentiated keratinocytes, generating superoxide anion and hydrogen peroxide as well as increased protein oxidation which was greater in differentiated cells.