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Honghong Yao

Researcher at Southeast University

Publications -  111
Citations -  6563

Honghong Yao is an academic researcher from Southeast University. The author has contributed to research in topics: Autophagy & Protein kinase B. The author has an hindex of 39, co-authored 99 publications receiving 4084 citations. Previous affiliations of Honghong Yao include Nantong University & University of Nebraska Medical Center.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Circular RNA and its mechanisms in disease: From the bench to the clinic.

TL;DR: Although their exact roles and mechanisms of gene regulation remain to be clarified, circRNAs have potential applications as disease biomarkers and novel therapeutic targets.
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Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.

TL;DR: A critical role is demonstrated for circular RNA DLGAP4 (circDLG AP4), a novel circular RNA originally identified as a sponge for microRNA-143 (miR-143), in ischemic stroke outcomes, in what is the first report describing the efficacy of circRNA injection in an isChemic stroke model.
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Novel insight into circular RNA HECTD1 in astrocyte activation via autophagy by targeting MIR142-TIPARP: implications for cerebral ischemic stroke

TL;DR: The results of this study indicate thatcircHECTD1 and its coupling mechanism are involved in cerebral ischemia, thus providing translational evidence that circHectD1 can serve as a novel biomarker of and therapeutic target for stroke.
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Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124–2HG

TL;DR: It is shown that the circular RNA HIPK2 (circHIPK2) functions as an endogenous microRNA-124 (MIR 124–2HG) sponge to sequester MIR124– 2HG and inhibit its activity, resulting in increased sigma non-opioid intracellular receptor 1 (SIGMAR1/OPRS1) expression.