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J. Thomas Sanderson

Researcher at Institut national de la recherche scientifique

Publications -  66
Citations -  4787

J. Thomas Sanderson is an academic researcher from Institut national de la recherche scientifique. The author has contributed to research in topics: Aromatase & LNCaP. The author has an hindex of 29, co-authored 66 publications receiving 3604 citations. Previous affiliations of J. Thomas Sanderson include City University of Hong Kong & Université du Québec.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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The Steroid Hormone Biosynthesis Pathway as a Target for Endocrine-Disrupting Chemicals

TL;DR: This review aims to provide a comprehensive overview of the state of knowledge regarding the mechanisms by which chemicals interfere with the function of steroidogenic enzymes in various tissues and organisms.
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Induction and inhibition of aromatase (CYP19) activity by various classes of pesticides in H295R human adrenocortical carcinoma cells.

TL;DR: Time- response curves for cAMP induction and concentration-response curves for aromatase induction by vinclozolin, atrazine, and IBMX were similar, suggesting that the mechanism of aromat enzyme induction by these pesticides is mediated through inhibition of phosphodiesterase activity.
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Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes.

TL;DR: The findings indicate that the estrogenic effects associated with the triazine herbicides in vivo are not estrogen receptor-mediated, but may be explained partly by their ability to induce aromatase in vitro.
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Comparison of Ah Receptor-Mediated Luciferase and Ethoxyresorufin-O-deethylase Induction in H4IIE Cells: Implications for Their Use as Bioanalytical Tools for the Detection of Polyhalogenated Aromatic Hydrocarbons

TL;DR: H4IIE-luc cells are supported as an alternative bioanalytical tool to the wild-type cells for the detection of Ah agonists in environmental samples and an improved and down-scaled method for the H4IIe-wt bioassay is reported which allows for the rapid screening of environmental samples for Ah-active PhAHs.