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Thomas Pulinilkunnil

Researcher at Dalhousie University

Publications -  92
Citations -  5865

Thomas Pulinilkunnil is an academic researcher from Dalhousie University. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 36, co-authored 91 publications receiving 4159 citations. Previous affiliations of Thomas Pulinilkunnil include Beth Israel Deaconess Medical Center & University of British Columbia.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Morgan D. Fullerton, +19 more
- 01 Dec 2013 - 
TL;DR: It is established that inhibitory phosphorylation of Acc by Ampk is essential for the control of lipid metabolism and, in the setting of obesity, for metformin-induced improvements in insulin action.
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Nicotinamide N -methyltransferase knockdown protects against diet-induced obesity

Daniel Kraus, +18 more
- 10 Apr 2014 - 
TL;DR: Nicotinamide N-methyltransferase (NNMT) is a novel regulator of histone methylation, polyamine flux and NAD+-dependent SIRT1 signalling, and is a unique and attractive target for treating obesity and type 2 diabetes.
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Short Communication: Ischemia/Reperfusion Tolerance Is Time-of-Day–Dependent: Mediation by the Cardiomyocyte Circadian Clock

David J. Durgan, +9 more
- 19 Feb 2010 - 
TL;DR: In this article, the authors investigate whether time of day of an ischemic insult influences clinically relevant outcomes in mice and expose a profound time-of-day dependence for I/R tolerance, which is mediated by the cardiomyocyte circadian clock.
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Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion

Sanjoy Ghosh, +7 more
- 01 Apr 2005 - 
TL;DR: It is suggested for the first time that mGSH is crucial for modulating the cell suicide program in short-term diabetic rat hearts.