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Cristiana Perrotta

Researcher at University of Milan

Publications -  74
Citations -  4125

Cristiana Perrotta is an academic researcher from University of Milan. The author has contributed to research in topics: Acid sphingomyelinase & Autophagy. The author has an hindex of 31, co-authored 69 publications receiving 2796 citations. Previous affiliations of Cristiana Perrotta include University of Calabria.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Acid sphingomyelinase activity triggers microparticle release from glial cells.

Fabio Bianco, +11 more
- 22 Apr 2009 - 
TL;DR: The results represent the first demonstration that activation of acid sphingomyelinase is necessary and sufficient for microparticle release from glial cells and define key molecular effectors of microparticles formation and IL‐1β release, thus, opening new strategies for the treatment of neuroinflammatory diseases.
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Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism

Flavia Antonucci, +11 more
- 07 Mar 2012 - 
TL;DR: Analysis of spontaneous release of glutamate in neurons exposed to MVs found a dose‐dependent increase in miniature excitatory postsynaptic current (mEPSC) frequency without changes in mEpsC amplitude, and identifies microglia‐derived MVs as a new mechanism by which microglian influence synaptic activity.
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Nitric oxide release combined with nonsteroidal antiinflammatory activity prevents muscular dystrophy pathology and enhances stem cell therapy

Silvia Brunelli, +12 more
- 02 Jan 2007 - 
TL;DR: In both models, HCT 1026 significantly ameliorated the morphological, biochemical, and functional phenotype in the absence of secondary effects, efficiently slowing down disease progression and setting the stage for combined therapies with donor or autologous, genetically corrected stem cells.
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The thyroid hormone triiodothyronine controls macrophage maturation and functions: protective role during inflammation.

Cristiana Perrotta, +7 more
- 01 Jan 2014 - 
TL;DR: The data suggest that the anti-inflammatory effect of T3 is coupled to the modulation of peritoneal macrophage content, in a context not fully explained by the M1/M2 framework.