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Tomokazu Murakawa

Researcher at King's College London

Publications -  34
Citations -  3347

Tomokazu Murakawa is an academic researcher from King's College London. The author has contributed to research in topics: Pressure overload & Autophagy. The author has an hindex of 13, co-authored 32 publications receiving 2067 citations. Previous affiliations of Tomokazu Murakawa include Osaka University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

Takafumi Oka, +16 more
- 10 May 2012 - 
TL;DR: It is shown that mitochondrial DNA that escapes from autophagy cell-autonomously leads to Toll-like receptor (TLR) 9-mediated inflammatory responses in cardiomyocytes and is capable of inducing myocarditis and dilated cardiopathy in DNase II-deficient mice.
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Inhibition of autophagy in the heart induces age-related cardiomyopathy.

Manabu Taneike, +16 more
- 01 Jul 2010 - 
TL;DR: The results suggest that continuous constitutive autophagy has a crucial role in maintaining cardiac structure and function and the Atg5-deficient mice began to die after the age of 6 months.
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Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation.

Tomokazu Murakawa, +19 more
- 06 Jul 2015 - 
TL;DR: Bcl2-L-13 induces mitochondrial fragmentation in the absence of Drp1, while it induces mitophagy in Parkin-deficient cells and offers insights into mitochondrial quality control in mammalian cells.
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BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32.

Kinya Otsu, +2 more
- 20 Aug 2015 - 
TL;DR: It is demonstrated that BCL2L13 (BCL2-like 13 [apoptosis facilitator]) is a functional mammalian homolog of Atg32, which opens a new chapter in mitophagy research.