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Dana L. Miller

Researcher at University of Washington

Publications -  33
Citations -  2101

Dana L. Miller is an academic researcher from University of Washington. The author has contributed to research in topics: Proteostasis & Hypoxia (medical). The author has an hindex of 14, co-authored 32 publications receiving 1134 citations. Previous affiliations of Dana L. Miller include Johns Hopkins University & Fred Hutchinson Cancer Research Center.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans

TL;DR: It is shown that nematodes exposed to H2S are apparently healthy and do not exhibit phenotypes consistent with metabolic inhibition, and studies suggest that SIR-2.1 activity may translate environmental change into physiological alterations that improve survival.
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Novel Roles for Saccharomyces cerevisiae Mitotic Spindle Motors

TL;DR: It is revealed that kinesin-related Kar3p and Kip3p are unique in that they perform roles both inside and outside the nucleus, and yeast cell viability could be supported by as few as two microtubule-based motors required for spindle structure and positioning.
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Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span

TL;DR: It is reported that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nonautonomous signal to the intestine, which results in activation of the xenobiotic detoxification enzyme flavin-containing monooxygenase-2 (FMO-2).
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C. Elegans Are Protected from Lethal Hypoxia by an Embryonic Diapause

TL;DR: It is suggested that the maternal perception of hypoxia stimulates a response to protect embryos in utero by inducing diapause, a natural form of suspended animation, which is likely to be an important strategy to improve offspring survival in harsh conditions and allow adults to find environments more suitable for reproductive success.