scispace - formally typeset
J

John Jia En Chua

Researcher at Agency for Science, Technology and Research

Publications -  31
Citations -  2688

John Jia En Chua is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Synaptic vesicle & Exocytosis. The author has an hindex of 15, co-authored 31 publications receiving 1378 citations. Previous affiliations of John Jia En Chua include National University of Singapore & Max Planck Society.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

SynGO : An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Frank Koopmans, +78 more
- 17 Jul 2019 - 
TL;DR: It is shown that synaptic genes are exceptionally well conserved and less tolerant to mutations than other genes, and among de novo variants associated with neurodevelopmental disorders, including schizophrenia.
Journal ArticleDOI

The GTPase Rab26 links synaptic vesicles to the autophagy pathway

Beyenech Binotti, +11 more
- 02 Feb 2015 - 
TL;DR: It is proposed that Rab26 selectively directs synaptic and secretory vesicles into preautophagosomal structures, suggesting the presence of a novel pathway for degradation of synaptic vesicle degradation.
Journal ArticleDOI

Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein.

Mads Grønborg, +8 more
- 06 Jan 2010 - 
TL;DR: It is concluded that SVs specific for different neurotransmitters share the majority of their protein constituents, with only few vesicle proteins showing preferences that are nonexclusive, thus confirming that the vesicular transporters are the only components essential for defining the neurotransmitter phenotype of a SV.
Journal ArticleDOI

Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses.

Janina Boyken, +5 more
- 24 Apr 2013 - 
TL;DR: It is concluded that the core machinery involved in vesicle docking and exocytosis does not show compositional differences between the two types of synapses.