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Martin Post

Researcher at University of Toronto

Publications -  288
Citations -  16644

Martin Post is an academic researcher from University of Toronto. The author has contributed to research in topics: Lung & Lung injury. The author has an hindex of 65, co-authored 271 publications receiving 14563 citations. Previous affiliations of Martin Post include Mount Sinai Hospital & Medical Research Council.

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

TL;DR: Examination of placental expression of hypoxia-inducible factor-1 (HIF-1), a master regulator of oxygen homeostasis, determined that expression of Hif-1alpha subunit during the first trimester of gestation parallels that of TGFbeta(3), an inhibitor of extravillous trophoblast differentiation.
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Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

TL;DR: It is reported that mutant mice lacking Gli2 function exhibit foregut defects, including stenosis of the oesophagus and trachea, as well as hypoplasia and lobulation defects of the lung, and it is suggested that mutations in GLI genes may be involved in humanForegut malformations.
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Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsia.

TL;DR: It is speculated that if oxygen tension fails to increase, or trophoblasts do not detect this increase, HIF-1alpha and TGFbeta3 expression remain high, resulting in shallow trophoblast invasion and predisposing the pregnancy to pre-eclampsia.